On Tuesday, the team behind the plan to bring the animals back to the Tandra announced what to say to Wali rats, which has a long reminder of the ounce of mammoth. The long fur was created by simultaneous modification of at least seven genes, all of which are with known connections to hair growth, color and/or structure.
But do not think that this is a type of mouse Memour hybrid. Most genetic changes were identified in the first mice, not mammoth. Therefore, the focus is on the fact that the team can simultaneously amend several genes.
Of mice and mummuts
The team of Colasal Bio Sciences has started several de -extension projects, including Doodo And ThylacineBut his flagship plan is huge. In all these cases, the plan is to get stem sales from close related species that have not been extinct, and amend the died species on the basis of changes based on the related genoms. In the case of Memouth, it means an elephant.
But the elephant recognizes large numbers of challenges, as the draft paper recognizes the new mice. Researchers acknowledged, “The 22 -month -old pregnancy period of elephants and their expanded reproductive timeline rapidly made experimental diagnosis.” “In addition, ethical reservations about the experimental manipulation of elephants, a risky species of complex social structures and high academic abilities need to be alanative alternative approach to practical testing.”
Therefore, he turned to a generation that has been used for more than a century for genetic experiences: mouse. We can manipulate all kinds of genetic diamonds in mice, and we have ways to use fetal stem cells to reach a new generation of mice.
For the purposes of testing, the mouse also has a very important advantage: searching for the variations that change its skin is easy. Over the century we have been using mice for research, people have seen and observed many changes that affect their skin, color, color, structure and length. In many of these cases, these changes have been identified due to changes in DNA.