In mice, the drug produced a permanent reduction in weekly weight during the six -week study period, while saving 100 % lean muscle mass.
In the first Human Pilot study of nine participants, the drug was not safe with no negative effect. The intestinal tissue samples were used to confirm that the coating is made and the body was cleaned within 24 hours. This study was not designed to evaluate weight loss, but blood tests suggest that after the drug was given, glucose levels and “appetite hormone” were low, while leptin levels, hunger -manning hormone levels were high.
“When the nutrients are later redirected to the intestines, you are activating the path that leads to support, energy costs and overall healthy, sustainable weight loss,” says Dhanda.
The results of the syntax bio in the animal also indicated the ability to lose weight without compromising the muscle mass, one of the current GLP-1 pharmaceutical concerns. Although weight loss is usually associated with numerous precision benefits, but there is Growing Conviction That the kind of severe weight loss can also lead to massive loss of lean muscles.
Obesity Medicine specialist and Professor Louis Arun, a professor of metabolic research at Wheel Cornell Medical College, says GLP -1s are very popular, but maybe they will not be fine for everyone. He predicted that there will be many medicines for obesity in the future of remote future, and the treatment will be more personal. “I think the compound of Santas fits as a cure that can be used soon. This is a type of thing you can use as a first -line medicine.” Irwin serves as the company’s clinical advisor.
Vladimir Kushir, director of Madison’s professor and director of Barratric Endoscopy at St. Louis, who is not included in the century, says the initial pilot’s data is encouraging, but such a small study is difficult to conclude. It is expected that the drug will feel full of people, but there may be some side effects like gastric bypass surgery. He says, “My expectation is that some of its digestive side effects, such as flowering and abdominal pain, are probably some diarrhea and nausea once it will come into a major study.”
There are early days for the technique of this novel, but if it proves effective, it can be an alternative or additional drug in GLP-1 drugs a day.
This story originally appeared Wired dot.