In 2012, physicians at Philadelphia Children’s Hospital treated Emily White Head, with 6 -year -old Lukemia, which has changed their body into immune cells. At that time, the treatment was experimental, but he worked: the cells targeted and removed the cancer. Thirteen years later, the White Head is still free from cancer.
Modified cells, say Car-t cellsAre a form of immuno therapy, where doctors convert parts of the immune system into cancer -attack devices. Almost five years after the White Head ReignFirst Car-T drugs were approved by the FDA, and at the same time it was healed. Immuno therapy More widely, as one of the latest cancer remedies. Today, there are seven FDA -approved CART treatments, which have been used to treat White Head.
Since then, however, Studies Car-T is linked to fatal complications due to toxic treatment, and the treatment has a difficult time to solve certain types of cancer, especially the solid tumors affecting breast and pancreatitis, though there are some small clinical trials. Start showing Positive results for solid cancer. “After a decade, a decade and a half, we arrive at the point that there are patients who respond, most patients still do not respond,” said George Calin, a researcher at the University of Texas.
Now experts say that new treatments are starting to cross the challenges that cannot be treated previously, which cannot provide a safe, more target supply to the tumor. These include medicines that contain radioactive substances, called radioferstical, which are used to diagnose or treat cancer. Drugs that can affect tumor growth or press the genes. And the treatment vaccine.
These methods have shown the promise in the lab, and researchers and companies are now performing various stages of human clinical trials to discover their effectiveness. And some promising treatment has also been approved by the Food and Drug Administration. The hope is that improving these strategies will eventually help the treatment of highly resistant cancer types.