Most polymer added plenty of lactic acid, which can also create an Easter bond. The cell usually has many lactic acids as it is one of the potential products of glucose metabolism. But the researchers knocked the gene, which encoded the basic enzyme that is produced with lactic acid, which dramatically cut the money contained in the polymer.
Researchers also tried several conditions, which shows that they can form a polymer, which was a mixture of two different amino acids monomers, and add non -amino acids to the mixture. By adding some additional enzymes i E -colony Stress, they managed to increase polymer production by more than 50 % by weight. He also showed that you can introduce the variation in the enzyme that does polymerization, and will result in maximum specific amino acids in the polymer.
Overall, the system they produce is significantly flexible, which is able to add a huge range of chemicals to a polymer. This should allow them to tune plastics as a result of many features. And, the bonds were formed by enzyme, resulting in the polymer will definitely be bioded.
However, some are negative. This process does not allow full control when joining the polymer. You can biased it towards a specific mixture of amino acids or other chemicals, but you cannot completely prevent the enzyme from adding random chemicals to a polymer at a rough level. Before adding to the manufacturing, there is also the problem of cleaning the polymer with all other cell components. Production is relatively slower than mass industrial production.
Therefore, it is not ready to handle plastic production globally. But this work does a great job to highlight the bio -manufacturing capacity.
Nature Chemical Biology, 2025. DOI: 10.1038/s41589-025-01842-2 For,,,,,,,,,, for,, for,,,, for,,,, for,,, for,,,, for,,,, for,,,, for,,, for,,, for,,, for,,, for,,,, for,,, for,,, for,,,, for,,, for,,,, for,,, for,,, for,,,, for,,, for,,, for,,,, for,,, for,,,, for,,, for,,,, for,,, for,,,, for,,, for,,,, for,,,, for,,,, for,,,, for,,,, for,,,, for,,,, for,,, for,,, for,,, for,,, for,,,,, for,,,, for,,,, for,,,, for,, for,.about DOIS,