Before an important point of development, the animal failed to close the wounds made by the kit, causing the two fetus parts to easily raise cells in the environment. To some extent, however, it was excellent survival, and the part of the fetus can regenerate the tail part. It tells us that the common signaling paths in the fetus are enough to advance the process.
But at this stage, the tail of the franc does not appear to be able to rebuild his head. But researchers found that they could stop WNT signaling in these previous pieces, and it was enough to develop the head.
Muscle deficiency
There is a possibility here that the vent signaling is widely active in the back of the fetal at this location, which blocks the structure of the previous structure. As an alternative, researchers speculate that this problem is with muscle cells that usually help manage the formation of stem cell -filled blastima, which is necessary to eliminate the regeneration process. Since the previous end of fetal is prepared before, they suggest that so many muscle cells cannot be easily done in the early stages of development.
They, to examine their assumptions, had some extraordinary experience. They started cutting the branches and saving them for 24 hours. At that time, they created a new wound after the end of the tail ended. At this point, the regeneration was able to move forward as usual, and the tails raised a new head. It is not certain that muscle cells are missing in the early stages, but this shows that there is some important development move in the tail within the 24 -hour window after the first cut.
The results reinforces the idea that the regeneration of large parts of the body requires the re -establishment of the gestures that offer the fetal organization in development. It becomes a bit complicated if they are currently working to manage the fetus. And it clearly shows that the cells needed to do this reorganization are not only put aside at the beginning of development, but it takes some time to appear instead. All this information will help to clarify how these animals manage such complex creation processes.
Current Biology, 2025. DOI: 10.1016/j.cub.2025.03.065 For,,,,,,,,,, for,, for,,,, for,,,, for,,, for,,,, for,,,, for,,,, for,,, for,,, for,,, for,,, for,,,, for,,, for,,, for,,,, for,,, for,,,, for,,, for,,, for,,,, for,,, for,,, for,,,, for,,, for,,,, for,,, for,,,, for,,, for,,,, for,,, for,,,, for,,,, for,,,, for,,,, for,,,, for,,,, for,,,, for,,, for,,, for,,, for,,, for,,,,, for,,,, for,,,, for,,,, for,, for,.about DOIS,